Mitogen-activated protein kinase 1 - 搜索结果

找到约 5 条 “Mitogen-activated protein kinase 1” 相关结果（用时 0.152 秒）

目录号	产品名称	中文名称	靶点
M52815	Mitogen-activated protein kinase 1	Mitogen-activated protein kinase 1	NF-κB
	Mitogen-activated protein kinase 1 (MAPK1) 可以激活下游 p38/NF-κB 通路。
M8200	SB 220025 trihydrochloride	SB 220025 trihydrochloride	Others
	SB 220025 is a potent, specific inhibitor of human p38 mitogen-activated protein (MAP) kinase, with an IC₅₀value of 60 nM and 50- to 1000-fold selectivity.
M20176	WAY-382818	WAY-382818	Others
	WAY-382818 has mitogen-activated protein kinase phosphatase-1 inhibitory activity.
M20713	DMX-5084	DMX-5084	MAPKAPK2/MAP3K/MAP4K
	DMX-5804 is a potent, orally active and selective inhibitor of Mitogen-activated protein kinase kinase kinase kinase-4 (MAP4K4) with IC50 of 3 nM for human MAP4K4. DMX-5804 is more potent on human MAP4K4 with pIC50 of 8.55 than MINK1/MAP4K6 and TNIK/MAP4K7 with pIC50 of 8.18 and 7.96, respectively.
M20734	(E/Z)-BCI	(E/Z)-BCI	Phosphatase
	BCI, NSC 150117
	(E/Z)-BCI (BCI, NSC 150117) is an inhibitor of dual specific phosphatase 1/6 (DUSP1/DUSP6) and mitogen-activated protein kinase with EC50 of 13.3 μM and 8.0 μM for DUSP6 and DUSP1 in cells, respectively. (E)-BCI induces apoptosis via generation of reactive oxygen species (ROS) and activation of intrinsic mitochondrial pathway in H1299 lung cancer cells.